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Ceefourin 1
CAS No. 315702-40-0
Ceefourin 1 ( —— )
产品货号. M22241 CAS No. 315702-40-0
Ceefourin 1 是一种高选择性多药耐药蛋白 4 (MRP4) 抑制剂。Ceefourin 1 和 Ceefourin 2 可抑制多种 MRP4 底物的转运。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥413 | 有现货 |
|
| 5MG | ￥648 | 有现货 |
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| 10MG | ￥988 | 有现货 |
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| 25MG | ￥2130 | 有现货 |
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| 50MG | ￥3313 | 有现货 |
|
| 100MG | ￥4828 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Ceefourin 1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Ceefourin 1 是一种高选择性多药耐药蛋白 4 (MRP4) 抑制剂。Ceefourin 1 和 Ceefourin 2 可抑制多种 MRP4 底物的转运。
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产品描述Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.Ceefourin 1 and Ceefourin 2, that inhibit transport of a broad range of MRP4 substrates, yet are highly selective for MRP4 over other ABC transporters, including P-glycoprotein (P-gp), ABCG2 (Breast Cancer Resistance Protein;?BCRP) and MRP1 (multidrug resistance protein 1;?ABCC1).?Both compounds are more potent MRP4 inhibitors in cellular assays than the most widely used inhibitor, MK-571, requiring lower concentrations to effect a comparable level of inhibition.?Furthermore, Ceefourin 1 and Ceefourin 2 have low cellular toxicity, and high microsomal and acid stability.?
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体外实验——
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体内实验——
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同义词——
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通路Endocrinology/Hormones
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靶点MRP
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受体MRP4
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研究领域——
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适应症——
化学信息
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CAS Number315702-40-0
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分子量294.42
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分子式C11H10N4S3
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (424.56 mM)
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SMILESS=C1N(C)C(CSC2=NC3=CC=CC=C3S2)=NN1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Cheung L , Flemming C L , Watt F , et al. High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)[J]. Biochemical Pharmacology, 2014, 91(1):97-108.
产品手册
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